The Chaperonin TRiC/CCT Inhibitor HSF1A Protects Cells from Intoxication with Pertussis Toxin

The Chaperonin TRiC/CCT Inhibitor HSF1A Protects Cells from Intoxication with Pertussis Toxin

Pertussis toxin (PT) is a bacterial AB<sub>5</sub>-toxin produced by <i>Bordetella pertussis</i> and a major molecular determinant of pertussis, also known as whooping cough, a highly contagious respiratory disease. In this study, we investigate the protective effects of the...

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Bibliographic Details
Main Authors: Jinfang Jia, Manuel Zoeschg, Holger Barth, Arto T. Pulliainen, Katharina Ernst
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Toxins
Subjects:
pertussis toxin
TRiC/CCT
chaperonin
cellular uptake
toxin inhibitor
AB-type toxin
Online Access:https://www.mdpi.com/2072-6651/16/1/36

Internet

https://www.mdpi.com/2072-6651/16/1/36

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