Antioxidant Role and Cardiolipin Remodeling by Redox-Activated Mitochondrial Ca<sup>2+</sup>-Independent Phospholipase A<sub>2</sub>γ in the Brain

Antioxidant Role and Cardiolipin Remodeling by Redox-Activated Mitochondrial Ca<sup>2+</sup>-Independent Phospholipase A<sub>2</sub>γ in the Brain

Mitochondrial Ca<sup>2+</sup>-independent phospholipase A<sub>2</sub>γ (iPLA<sub>2</sub>γ/PNPLA8) was previously shown to be directly activated by H<sub>2</sub>O<sub>2</sub> and release free fatty acids (FAs) for FA-dependent H<sup>+&...

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Bibliographic Details
Main Authors: Pavla Průchová, Klára Gotvaldová, Katarína Smolková, Lukáš Alán, Blanka Holendová, Jan Tauber, Alexander Galkin, Petr Ježek, Martin Jabůrek
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Antioxidants
Subjects:
mitochondria
phospholipase iPLA<sub>2</sub>γ/PNPLA8
adenine nucleotide translocase
redox homeostasis
cardiolipin remodeling
Online Access:https://www.mdpi.com/2076-3921/11/2/198

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https://www.mdpi.com/2076-3921/11/2/198

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