Characterization of the equine 2'-5' oligoadenylate synthetase 1 (<it>OAS1</it>) and ribonuclease L (<it>RNASEL</it>) innate immunity genes
<p>Abstract</p> <p>Background</p> <p>The mammalian OAS/RNASEL pathway plays an important role in antiviral host defense. A premature stop-codon within the murine <it>Oas1b </it>gene results in the increased susceptibility of mice to a number of flaviviruses,...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-09-01
|
| Series: | BMC Genomics |
| Online Access: | http://www.biomedcentral.com/1471-2164/8/313 |