Circulating brain-derived extracellular vesicles expressing neuroinflammatory markers are associated with HIV-related neurocognitive impairment

Circulating brain-derived extracellular vesicles expressing neuroinflammatory markers are associated with HIV-related neurocognitive impairment

BackgroundNeurocognitive impairment remains prevalent in people with HIV (PWH) despite long term virological suppression by antiretroviral therapy (ART) regimens. Systemic and neuro-inflammatory processes are suggested to contribute to the complex pathology leading to cognitive impairment in this po...

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Bibliographic Details
Main Authors: Erika G. Marques de Menezes, Jocelyn S. Liu, Scott A. Bowler, Leila B. Giron, Michelle L. D’Antoni, Cecilia M. Shikuma, Mohamed Abdel-Mohsen, Lishomwa C. Ndhlovu, Philip J. Norris
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
extracellular vesicles
monocytes
neurons
neurocognitive impairment
human immunodeficiency virus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1033712/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1033712/full

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