Regulatory B Lymphocytes Colonize the Respiratory Tract of Neonatal Mice and Modulate Immune Responses of Alveolar Macrophages to RSV Infection in IL-10-Dependant Manner

Regulatory B Lymphocytes Colonize the Respiratory Tract of Neonatal Mice and Modulate Immune Responses of Alveolar Macrophages to RSV Infection in IL-10-Dependant Manner

Respiratory syncytial virus (RSV) is the prevalent pathogen of lower respiratory tract infections in children. The presence of neonatal regulatory B lymphocytes (nBreg) has been associated with a poor control of RSV infection in human newborns and with bronchiolitis severity. So far, little is known...

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Bibliographic Details
Main Authors: Daphné Laubreton, Carole Drajac, Jean-François Eléouët, Marie-Anne Rameix-Welti, Richard Lo-Man, Sabine Riffault, Delphyne Descamps
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Viruses
Subjects:
respiratory syncytial virus
neonates
age-dependent replication
lungs
innate immunity
immunoregulation
Online Access:https://www.mdpi.com/1999-4915/12/8/822

Internet

https://www.mdpi.com/1999-4915/12/8/822

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