Replenishment of mitochondrial Na+ and H+ by ionophores potentiates cutaneous wound healing in diabetes

Replenishment of mitochondrial Na+ and H+ by ionophores potentiates cutaneous wound healing in diabetes

Diabetic foot ulcer (DFU) is a highly morbid complication in patients with diabetes mellitus, necessitating the development of innovative pharmaceuticals to address unmet medical needs. Sodium ion (Na+) is a well-established mediator for membrane potential and osmotic equilibrium. Recently, Na+ tran...

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Bibliographic Details
Main Authors: Liangliang Bai, Linping Wu, Changsheng Zhang, Zhiwen Liu, Liang Ma, Jing Ni, Dezhen He, Mingxuan Zhu, Shaoyong Peng, Xiaoxia Liu, Huichuan Yu, Yuhe Lei, Yanxin Luo, Yu Zhang, Xiaolin Wang, Gang Wei, Yingjie Li
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Materials Today Bio
Subjects:
Na+
Ionophores
Skin wound healing
Reactive oxygen species
Mitochondrial energy metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424001157

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http://www.sciencedirect.com/science/article/pii/S2590006424001157

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