Fluoxetine potentiates methylphenidate-induced behavioral responses: Enhanced locomotion or stereotypies and facilitated acquisition of cocaine self-administration

The medical psychostimulant methylphenidate (MP) is used to treat attention-deficit hyperactivity disorder and recreationally as a “cognitive enhancer”. MP is a dopamine reuptake inhibitor, but does not affect serotonin. Serotonin contributes to addiction-related gene regulation and behavior. Previo...

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Bibliographic Details
Main Authors: Lorissa Lamoureux, Joel A. Beverley, Michela Marinelli, Heinz Steiner
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Addiction Neuroscience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2772392523000743