Therapeutic potential of extracellular vesicles derived from cardiac progenitor cells in rodent models of chemotherapy-induced cardiomyopathy

Therapeutic potential of extracellular vesicles derived from cardiac progenitor cells in rodent models of chemotherapy-induced cardiomyopathy

BackgroundCurrent treatments of chemotherapy-induced cardiomyopathy (CCM) are of limited efficacy. We assessed whether repeated intravenous injections of human extracellular vesicles from cardiac progenitor cells (EV-CPC) could represent a new therapeutic option and whether EV manufacturing accordin...

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Main Authors: Manon Desgres, Bruna Lima Correa, Lorena Petrusca, Gwennhael Autret, Chloé Pezzana, Céline Marigny, Chloé Guillas, Valérie Bellamy, José Vilar, Marie-Cécile Perier, Florent Dingli, Damarys Loew, Camille Humbert, Jérôme Larghero, Guillaume Churlaud, Nisa Renault, Pierre Croisille, Albert Hagège, Jean-Sébastien Silvestre, Philippe Menasché
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
cardiovascular progenitor
extracellular vesicles
chemotherapy-induced cardiomyopathy
cardiac strain
cardio-oncology
regenerative medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1206279/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2023.1206279/full

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