Systemic immune modulation by stereotactic radiotherapy in early-stage lung cancer

Abstract We performed a prospective study of circulating immune cell changes after stereotactic body radiotherapy (SBRT) in 50 early-stage NSCLC patients. We found no significant increase in CD8+ cytotoxic T lymphocytes at first follow-up (the primary endpoint) but detected a significant increase in...

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Bibliographic Details
Main Authors: Eleni Gkika, Elke Firat, Sonja Adebahr, Erika Graf, Ilinca Popp, Gianluca Radicioni, Simon S. Lo, Ursula Nestle, Nils H. Nicolay, Gabriele Niedermann, Dan G. Duda, Anca-L. Grosu
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-023-00358-z