Bi- and Tri-Specific T Cell Engager-Armed Oncolytic Viruses: Next-Generation Cancer Immunotherapy

Bi- and Tri-Specific T Cell Engager-Armed Oncolytic Viruses: Next-Generation Cancer Immunotherapy

Oncolytic viruses (OVs) are potent anti-cancer biologics with a bright future, having substantial evidence of efficacy in patients with cancer. Bi- and tri-specific antibodies targeting tumor antigens and capable of activating T cell receptor signaling have also shown great promise in cancer immunot...

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Bibliographic Details
Main Authors: Zong Sheng Guo, Michael T. Lotze, Zhi Zhu, Walter J. Storkus, Xiao-Tong Song
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Biomedicines
Subjects:
oncolytic virus
bispecific antibody
trispecific antibody
bispecific T cell engager
trispecific T cell engager
tumor antigen-specific T cells
Online Access:https://www.mdpi.com/2227-9059/8/7/204

Internet

https://www.mdpi.com/2227-9059/8/7/204

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