Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozinResearch in context

Liver autophagy-induced valine and leucine in plasma reflect the metabolic effect of sodium glucose co-transporter 2 inhibitor dapagliflozinResearch in context

Summary: Background: Sodium glucose co-transporter 2 (SGLT2) inhibitors are anti-diabetic drugs for type 2 diabetes that lower blood glucose levels and body weight. It is of special interest that SGLT2 inhibitors also improve liver metabolism and fatty liver. Liver is an important organ in regulati...

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Bibliographic Details
Main Authors: Futoshi Furuya, Yoshihito Fujita, Naomi Matsuo, Hiroto Minamino, Yasuo Oguri, Nozomi Isomura, Kaori Ikeda, Kohei Takesue, Ying Li, Aki Kondo, Fumika Mano, Nobuya Inagaki
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:EBioMedicine
Subjects:
Sodium glucose co-transporter 2 (SGLT2) inhibitor
Diabetes
Liver
Autophagy
Branched chain amino acids (BCAAs)
Biomarker
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422005242

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http://www.sciencedirect.com/science/article/pii/S2352396422005242

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