The effect of whole blood logistics on neutrophil non-specific activation and kinetics ex vivo

Abstract While the exquisite sensitivity of neutrophils enables their rapid response to infection in vivo; this same sensitivity complicates the ex vivo study of neutrophils. Handling of neutrophils ex vivo is fraught with unwanted heterogeneity and alterations that can diminish the reproducibility...

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Bibliographic Details
Main Authors: Chao Li, Mehtab Farooqui, Ravi Chandra Yada, Joseph B. Cai, Anna Huttenlocher, David J. Beebe
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50813-x