Gemtuzumab Ozogamicin in Acute Myeloid Leukemia: Efficacy, Toxicity, and Resistance Mechanisms—A Systematic Review

Gemtuzumab Ozogamicin in Acute Myeloid Leukemia: Efficacy, Toxicity, and Resistance Mechanisms—A Systematic Review

Acute myeloid leukemia (AML) is a diverse group of leukemias characterized by the uncontrolled proliferation of clonal neoplastic hematopoietic precursor cells with chromosomal rearrangements and multiple gene mutations and the impairment of normal hematopoiesis. Current efforts to improve AML outco...

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Bibliographic Details
Main Authors: Aurelia Collados-Ros, Manuel Muro, Isabel Legaz
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Biomedicines
Subjects:
acute myeloid leukemia
CD33
gemtuzumab ozogamicin
toxicity
epigenetic therapeutics
Online Access:https://www.mdpi.com/2227-9059/12/1/208

Internet

https://www.mdpi.com/2227-9059/12/1/208

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