DNA methylation profile of Aire-deficient mouse medullary thymic epithelial cells
<p>Abstract</p> <p>Background</p> <p>Medullary thymic epithelial cells (mTECs) are characterized by ectopic expression of self-antigens during the establishment of central tolerance. The autoimmune regulator (Aire), which is specifically expressed in mTECs, is responsib...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-11-01
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Series: | BMC Immunology |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1471-2172/13/58 |