DNA methylation profile of Aire-deficient mouse medullary thymic epithelial cells

<p>Abstract</p> <p>Background</p> <p>Medullary thymic epithelial cells (mTECs) are characterized by ectopic expression of self-antigens during the establishment of central tolerance. The autoimmune regulator (Aire), which is specifically expressed in mTECs, is responsib...

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Bibliographic Details
Main Authors: Wu Guoying, Hirabayashi Keiji, Sato Shinya, Akiyama Nobuko, Akiyama Taishin, Shiota Kunio, Yagi Shintaro
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Immunology
Subjects:
Online Access:http://www.biomedcentral.com/1471-2172/13/58