Dynamic changes in the tumor microenvironment under the effect of estradiol as a diagnostic tool and target for targeted cancer therapy

Activation of the estrogen receptor-α (ER-α) signaling pathway is a significant factor in the initiation of carcinogenesis in various types of tumors due to the genomic and non-genomic effects of estradiol in cancer cells. However, data on the expression of ER-α and aromatase on stromal and immune c...

Full description

Bibliographic Details
Main Authors: A. I. Stukan, A. Yu. Goryainova, A. A. Meshcheryakov, V. A. Porkhanov, R. A. Murashko, S. V. Sharov, V. N. Bodnya
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2022-04-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/4713