Biodistribution, biocompatibility and targeted accumulation of magnetic nanoporous silica nanoparticles as drug carrier in orthopedics

Abstract Background In orthopedics, the treatment of implant-associated infections represents a high challenge. Especially, potent antibacterial effects at implant surfaces can only be achieved by the use of high doses of antibiotics, and still often fail. Drug-loaded magnetic nanoparticles are very...

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Bibliographic Details
Main Authors: Hilke Catherina Janßen, Nina Angrisani, Stefan Kalies, Florian Hansmann, Manfred Kietzmann, Dawid Peter Warwas, Peter Behrens, Janin Reifenrath
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-020-0578-8