Spatial heterogeneity of tumor microenvironment influences the prognosis of clear cell renal cell carcinoma

Spatial heterogeneity of tumor microenvironment influences the prognosis of clear cell renal cell carcinoma

Abstract Background Clear cell renal cell carcinoma (ccRCC) is an immunologically and histologically diverse tumor. However, how the structural heterogeneity of tumor microenvironment (TME) affects cancer progression and treatment response remains unclear. Hence, we characterized the TME architectur...

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Bibliographic Details
Main Authors: Dawei Zhang, Yuanli Ni, Yongquan Wang, Juan Feng, Na Zhuang, Jiatao Li, Limei Liu, Wenhao Shen, Ji Zheng, Wei Zheng, Cheng Qian, Juanjuan Shan, Zhansong Zhou
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Translational Medicine
Subjects:
Clear cell renal cell carcinoma
Tumor microenvironment
Immune architecture
Cellular neighborhood
Survival
Online Access:https://doi.org/10.1186/s12967-023-04336-8

Internet

https://doi.org/10.1186/s12967-023-04336-8

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