The proprotein convertase BLI-4 promotes collagen secretion prior to assembly of the Caenorhabditis elegans cuticle.

Some types of collagens, including transmembrane MACIT collagens and C. elegans cuticle collagens, are N-terminally cleaved at a dibasic site that resembles the consensus for furin or other proprotein convertases of the subtilisin/kexin (PCSK) family. Such cleavage may release transmembrane collagen...

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Bibliographic Details
Main Authors: Susanna K Birnbaum, Jennifer D Cohen, Alexandra Belfi, John I Murray, Jennifer R G Adams, Andrew D Chisholm, Meera V Sundaram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-09-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010944&type=printable