Impaired hepatitis C virus-specific T cell responses and recurrent hepatitis C virus in HIV coinfection.

Hepatitis C virus (HCV)-specific T cell responses are critical for spontaneous resolution of HCV viremia. Here we examined the effect of a lymphotropic virus, HIV-1, on the ability of coinfected patients to maintain spontaneous control of HCV infection.We measured T cell responsiveness by lymphoprol...

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Bibliographic Details
Main Authors: Arthur Y Kim, Julian Schulze zur Wiesch, Thomas Kuntzen, Joerg Timm, Daniel E Kaufmann, Jared E Duncan, Andrea M Jones, Alysse G Wurcel, Benjamin T Davis, Rajesh T Gandhi, Gregory K Robbins, Todd M Allen, Raymond T Chung, Georg M Lauer, Bruce D Walker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-12-01
Series:PLoS Medicine
Online Access:http://europepmc.org/articles/PMC1705826?pdf=render