Sex Disparities in <i>MGMT</i> Promoter Methylation and Survival in Glioblastoma: Further Evidence from Clinical Cohorts

Introduction: Recent studies suggest an overrepresentation of <i>MGMT</i> promoter methylated tumors in females with <i>IDH</i>wt glioblastoma (GBM) compared to males, with a subsequent better response to alkylating treatment. Methods: To reveal sex-bound associations that ma...

Full description

Bibliographic Details
Main Authors: Anja Smits, Malgorzata Lysiak, Andreas Magnusson, Johan Rosell, Peter Söderkvist, Annika Malmström
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/4/556