The influences of microbial colonisation and germ-free status on the chicken TCRβ repertoire

Microbial colonisation is paramount to the normal development of the immune system, particularly at mucosal sites. However, the relationships between the microbiome and the adaptive immune repertoire have mostly been explored in rodents and humans. Here, we report a high-throughput sequencing analys...

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Bibliographic Details
Main Authors: Stefan Dascalu, Stephen G. Preston, Robert J. Dixon, Patrik G. Flammer, Steven Fiddaman, Amy Boyd, Joshua E. Sealy, Jean-Remy Sadeyen, Bernd Kaspers, Philippe Velge, Munir Iqbal, Michael B. Bonsall, Adrian L. Smith
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1052297/full