Concordance in detection of microsatellite instability by PCR and NGS in routinely processed tumor specimens of several cancer types

Abstract Background Microsatellite instability (MSI) occurs in several cancer types and is commonly used for prognosis and as a predictive biomarker for immune checkpoint therapy. Methods We analyzed n = 263 formalin‐fixed paraffin‐embedded (FFPE) tumor specimens (127 colorectal cancer (CRC), 55 end...

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Bibliographic Details
Main Authors: Stephan Bartels, Isabel Grote, Madeleine Wagner, Jannik Boog, Elisa Schipper, Tanja Reineke‐Plaass, Hans Kreipe, Ulrich Lehmann
Format: Article
Language:English
Published: Wiley 2023-08-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.6293