Computed tomography and photoacoustic imaging guided photodynamic therapy against breast cancer based on mesoporous platinum with insitu oxygen generation ability

Computed tomography and photoacoustic imaging guided photodynamic therapy against breast cancer based on mesoporous platinum with insitu oxygen generation ability

Photodynamic therapy (PDT) has been widely used in cancer treatment. However, hypoxia in most solid tumors seriously restricts the efficacy of PDT. To improve the hypoxic microenvironment, we designed a novel mesoporous platinum (mPt) nanoplatform to catalyze hydrogen peroxide (H2O2) within the tumo...

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Bibliographic Details
Main Authors: Lingyan Zhang, Mifang Li, Quan Zhou, Meng Dang, Yuxia Tang, Shouju Wang, Jijun Fu, Zhaogang Teng, Guangming Lu
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Mesoporous platinum
Photodynamic therapy
Tumor hypoxia
Photoacoustic imaging
Computed tomography imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383520305852

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http://www.sciencedirect.com/science/article/pii/S2211383520305852

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