Short-term senolytic treatment: a paradigm to promote fracture repair during aging

Increased age is blamed for a wide range of bone physiological changes, and although the underlying mechanisms affecting the decreased capacity for fracture healing are not fully understood, they are clearly linked to changes at the cellular level. Recent evidence suggests potential roles of senesce...

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Bibliographic Details
Main Authors: Isabel Beerman, Nathan Basisty, Rafael de Cabo
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-04-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI158871