Immunocheckpoint Inhibitors in Microsatellite-Stable or Proficient Mismatch Repair Metastatic Colorectal Cancer: Are We Entering a New Era?

Colorectal cancer (CRC) is the third most frequent cancer and the second leading cause of cancer-related deaths in Europe. About 5% of metastatic CRC (mCRC) are characterized by high microsatellite instability (MSI) due to a deficient DNA mismatch repair (dMMR), and this condition has been related t...

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Bibliographic Details
Main Authors: Laura Matteucci, Alessandro Bittoni, Graziana Gallo, Laura Ridolfi, Alessandro Passardi
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/21/5189