Regulatory pathways and drugs associated with ferroptosis in tumors

Regulatory pathways and drugs associated with ferroptosis in tumors

Abstract Ferroptosis is a type of cell death that depends on iron and reactive oxygen species (ROS). The accumulation of iron and lipid peroxidation primarily initiates oxidative membrane damage during ferroptosis. The core molecular mechanism of ferroptosis includes the regulation of oxidation and...

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Bibliographic Details
Main Authors: Dan Wang, Le Tang, Yijie Zhang, Guili Ge, Xianjie Jiang, Yongzhen Mo, Pan Wu, Xiangying Deng, Lvyuan Li, Sicheng Zuo, Qijia Yan, Shanshan Zhang, Fuyan Wang, Lei Shi, Xiayu Li, Bo Xiang, Ming Zhou, Qianjin Liao, Can Guo, Zhaoyang Zeng, Wei Xiong, Zhaojian Gong
Format: Article
Language:English
Published: Nature Publishing Group 2022-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-04927-1

Internet

https://doi.org/10.1038/s41419-022-04927-1

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