Evaluation of the neurological safety of epidurally-administered pregabalin in rats
BackgroundThe primary site of action of pregabalin, i.e. the α-2-δ subunit of the voltage-dependent calcium channel, is located at the dorsal root ganglion and dorsal horn of the spinal cord. Therefore, the epidural administration of pregabalin could have advantages over oral administration. However...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Korean Society of Anesthesiologists
2012-01-01
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Series: | Korean Journal of Anesthesiology |
Subjects: | |
Online Access: | http://ekja.org/upload/pdf/kjae-62-57.pdf |