Evaluation of the neurological safety of epidurally-administered pregabalin in rats

BackgroundThe primary site of action of pregabalin, i.e. the α-2-δ subunit of the voltage-dependent calcium channel, is located at the dorsal root ganglion and dorsal horn of the spinal cord. Therefore, the epidural administration of pregabalin could have advantages over oral administration. However...

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Bibliographic Details
Main Authors: Jeong Rim Lee, Pyung-Bok Lee, Gheeyoung Choe, Sang Chul Lee, Hyo Min Lee, Eunjung Kim, Yong Chul Kim
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2012-01-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kjae-62-57.pdf