Vagus nerve stimulation in the non-human primate: implantation methodology, characterization of nerve anatomy, target engagement and experimental applications

Abstract Background Vagus nerve stimulation (VNS) is a FDA approved therapy regularly used to treat a variety of neurological disorders that impact the central nervous system (CNS) including epilepsy and stroke. Putatively, the therapeutic efficacy of VNS results from its action on neuromodulatory c...

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Bibliographic Details
Main Authors: Aaron J. Suminski, Abigail Z. Rajala, Rasmus M. Birn, Ellie M. Mueller, Margaret E. Malone, Jared P. Ness, Caitlyn Filla, Kevin Brunner, Alan B. McMillan, Samuel O. Poore, Justin C. Williams, Dhanabalan Murali, Andrea Brzeczkowski, Samuel A. Hurley, Aaron M. Dingle, Weifeng Zeng, Wendell B. Lake, Kip A. Ludwig, Luis C. Populin
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Bioelectronic Medicine
Subjects:
Online Access:https://doi.org/10.1186/s42234-023-00111-8