Inference of Cancer Progression With Probabilistic Graphical Model From Cross-Sectional Mutation Data

With the advance of high-throughput sequencing technologies, a great amount of somatic mutation data in cancer have been produced, allowing deep analyzing tumor pathogenesis. However, the majority of these data are cross-sectional rather than temporal, and it is difficulty to infer the temporal orde...

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Bibliographic Details
Main Authors: Wei Zhang, Shu-Lin Wang
Format: Article
Language:English
Published: IEEE 2018-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/8338000/