Repurposed Drugs That Activate Autophagy in Filarial Worms Act as Effective Macrofilaricides

Repurposed Drugs That Activate Autophagy in Filarial Worms Act as Effective Macrofilaricides

Onchocerciasis and lymphatic filariasis are two neglected tropical diseases caused by filarial nematodes that utilize insect vectors for transmission to their human hosts. Current control strategies are based on annual or biannual mass drug administration (MDA) of the drugs Ivermectin or Ivermectin...

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Bibliographic Details
Main Authors: Denis Voronin, Nancy Tricoche, Ricardo Peguero, Anna Maria Kaminska, Elodie Ghedin, Judy A. Sakanari, Sara Lustigman
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Pharmaceutics
Subjects:
<i>Wolbachia</i>
autophagy
repurposed drugs
filarial diseases
macrofilaricidal drugs
Online Access:https://www.mdpi.com/1999-4923/16/2/256

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https://www.mdpi.com/1999-4923/16/2/256

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