Is aryl hydrocarbon receptor antagonism after ischemia effective in alleviating acute hepatic ischemia-reperfusion injury in rats?

Is aryl hydrocarbon receptor antagonism after ischemia effective in alleviating acute hepatic ischemia-reperfusion injury in rats?

Aryl hydrocarbon receptors (AhRs) have been reported to be important mediators of ischemic injury in the brain. Furthermore, the pharmacological inhibition of AhR activation after ischemia has been shown to attenuate cerebral ischemia-reperfusion (IR) injury. Here, we investigated whether AhR antago...

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Bibliographic Details
Main Authors: Jae-Im Kwon, Hwon Heo, Yeon Ji Chae, Joongkee Min, Do-Wan Lee, Sang Tae Kim, Monica Young Choi, Yu Sub Sung, Kyung Won Kim, Yoonseok Choi, Dong Cheol Woo, Chul-Woong Woo
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Heliyon
Subjects:
Liver
Ischemia
Reperfusion
Aryl hydrocarbon receptor
Magnetic resonance imaging
L-kynurenine
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023028037

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http://www.sciencedirect.com/science/article/pii/S2405844023028037

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