Spi-B alleviates food allergy by securing mucosal barrier and immune tolerance in the intestine

Spi-B alleviates food allergy by securing mucosal barrier and immune tolerance in the intestine

Food allergy is a type I allergic reaction induced by mast cells and is mainly activated by allergen-specific immunoglobulin (Ig)E. Spi-B is an E26-transformation-specific (Ets) family transcription factor essential for the differentiation and functional maturation of several immune cell subsets, in...

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Bibliographic Details
Main Authors: Narumi Ishihara, Yutaka Nakamura, Kyosuke Yakabe, Seiga Komiyama, Yumiko Fujimura, Tsuneyasu Kaisho, Shunsuke Kimura, Koji Hase
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Allergy
Subjects:
Spi-B
food allergy
epithelial barrier
IgE
oral tolerance
Online Access:https://www.frontiersin.org/articles/10.3389/falgy.2022.996657/full

Internet

https://www.frontiersin.org/articles/10.3389/falgy.2022.996657/full

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