PARP1 mediated PARylation contributes to myogenic progression and glucocorticoid transcriptional response
Abstract The ADP-ribosyltransferase, PARP1 enzymatically generates and applies the post-translational modification, ADP-Ribose (ADPR). PARP1 roles in genome maintenance are well described, but recent work highlights roles in many fundamental processes including cellular identity and energy homeostas...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-04-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-023-01420-2 |