Potency evaluation of unfractionated heparins commercialized in Brazil through anti-factor Xa and anti-factor IIa chromogenic tests and coagulation assay

Introduction: Heparin is a drug that has anticoagulant activity, binding to antithrombin and accelerating the rate of inhibition of several proteases involved in the coagulation process. In the 2000s, the world market faced a troubled period regarding heparins after reports of allergic reactions an...

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Bibliographic Details
Main Authors: Renata Jurema Medeiros, Nathália Pessoa Gonçalves, Magno Maciel Magalhães, João Ferreira Martins, Tiago Savignon Cardoso Machado
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2023-05-01
Series:Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia
Subjects:
Online Access:https://visaemdebate.incqs.fiocruz.br/index.php/visaemdebate/article/view/1923