In Vitro Cytotoxicity and Spectral Analysis-Based Phytochemical Profiling of Methanol Extract of <i>Barleria hochstetteri,</i> and Molecular Mechanisms Underlying Its Apoptosis-Inducing Effect on Breast and Lung Cancer Cell Lines

In Vitro Cytotoxicity and Spectral Analysis-Based Phytochemical Profiling of Methanol Extract of <i>Barleria hochstetteri,</i> and Molecular Mechanisms Underlying Its Apoptosis-Inducing Effect on Breast and Lung Cancer Cell Lines

The objectives of this research were to carry out GC–MS and LC–MS-based phytochemical profiling of <i>Barleria hochstetteri</i>, as well as flow cytometry-based mechanistic investigations of the cytotoxic effect of its extracts against breast and lung cancer cell lines. This preclinical...

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Bibliographic Details
Main Authors: Saad Ahmed Alkahtani, Ali Mohamed Alshabi, Ibrahim Ahmed Shaikh, Mohamed A. A. Orabi, Basel A. Abdel-Wahab, Ismail A. Walbi, Mohammed Shafiuddin Habeeb, Masood Medleri Khateeb, Arun K. Shettar, Joy H. Hoskeri
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Separations
Subjects:
<i>Barleria hochstetteri</i>
cancer
apoptosis
DNA damage
caspase-3
Online Access:https://www.mdpi.com/2297-8739/9/10/298

Internet

https://www.mdpi.com/2297-8739/9/10/298

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