Reprogramming mechanism dissection and trophoblast replacement application in monkey somatic cell nuclear transfer

Abstract Somatic cell nuclear transfer (SCNT) successfully clones cynomolgus monkeys, but the efficiency remains low due to a limited understanding of the reprogramming mechanism. Notably, no rhesus monkey has been cloned through SCNT so far. Our study conducts a comparative analysis of multi-omics...

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Bibliographic Details
Main Authors: Zhaodi Liao, Jixiang Zhang, Shiyu Sun, Yuzhuo Li, Yuting Xu, Chunyang Li, Jing Cao, Yanhong Nie, Zhuoyue Niu, Jingwen Liu, Falong Lu, Zhen Liu, Qiang Sun
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43985-7