Dexmedetomidine versus haloperidol for sedation of non-intubated patients with hyperactive delirium during the night in a high dependency unit: study protocol for an open-label, parallel-group, randomized controlled trial (DEX-HD trial)

Dexmedetomidine versus haloperidol for sedation of non-intubated patients with hyperactive delirium during the night in a high dependency unit: study protocol for an open-label, parallel-group, randomized controlled trial (DEX-HD trial)

Abstract Background Delirium is common in critically ill patients. Haloperidol has long been used for the treatment of delirium. Dexmedetomidine has recently been used to treat delirium among intubated critically ill patients. However, the efficacy of dexmedetomidine for delirium in non-intubated cr...

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Bibliographic Details
Main Authors: Takuma Minami, Hirotoshi Watanabe, Takao Kato, Kaori Ikeda, Kentaro Ueno, Ai Matsuyama, Junya Maeda, Yoji Sakai, Hisako Harada, Akira Kuriyama, Kyohei Yamaji, Naoki Kitajima, Jun Kamei, Yudai Takatani, Yuki Sato, Yugo Yamashita, Toshiyuki Mizota, Shigeru Ohtsuru
Format: Article
Language:English
Published: BMC 2023-06-01
Series:BMC Anesthesiology
Subjects:
Agitation
Delirium
Haloperidol
Dexmedetomidine
Randomized controlled trial
Pharmacotherapy
Online Access:https://doi.org/10.1186/s12871-023-02158-1

Internet

https://doi.org/10.1186/s12871-023-02158-1

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