Vaccinia virus and peptide-receptor radiotherapy synergize to improve treatment of peritoneal carcinomatosis

Vaccinia virus and peptide-receptor radiotherapy synergize to improve treatment of peritoneal carcinomatosis

Tumor-specific overexpression of receptors enables a variety of targeted cancer therapies, exemplified by peptide-receptor radiotherapy (PRRT) for somatostatin receptor (SSTR)-positive neuroendocrine tumors. While effective, PRRT is restricted to tumors with SSTR overexpression. To overcome this lim...

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Bibliographic Details
Main Authors: Kathryn Ottolino-Perry, David Mealiea, Clara Sellers, Sergio A. Acuna, Fernando A. Angarita, Lili Okamoto, Deborah Scollard, Mihaela Ginj, Raymond Reilly, J. Andrea McCart
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Molecular Therapy: Oncolytics
Subjects:
oncolytic virus
virotherapy
peptide-receptor radiotherapy
vaccinia
colorectal cancer
somatostatin receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770523000268

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http://www.sciencedirect.com/science/article/pii/S2372770523000268

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