Recruitment of pre-dementia participants: main enrollment barriers in a longitudinal amyloid-PET study

Recruitment of pre-dementia participants: main enrollment barriers in a longitudinal amyloid-PET study

Abstract Background The mismatch between the limited availability versus the high demand of participants who are in the pre-dementia phase of Alzheimer’s disease (AD) is a bottleneck for clinical studies in AD. Nevertheless, potential enrollment barriers in the pre-dementia population are relatively...

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Main Authors: Ilse Bader, Ilona Bader, Isadora Lopes Alves, David Vállez García, Bruno Vellas, Bruno Dubois, Mercè Boada, Marta Marquié, Daniele Altomare, Philip Scheltens, Rik Vandenberghe, Bernard Hanseeuw, Michael Schöll, Giovanni B. Frisoni, Frank Jessen, Agneta Nordberg, Miia Kivipelto, Craig W. Ritchie, Oriol Grau-Rivera, José Luis Molinuevo, Lisa Ford, Andrew Stephens, Rossella Gismondi, Juan Domingo Gispert, Gill Farrar, Frederik Barkhof, Pieter Jelle Visser, Lyduine E. Collij, on behalf of the AMYPAD consortium
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Preclinical
Recruitment
Enrollment barriers
Amyloid PET
Clinical trial
Online Access:https://doi.org/10.1186/s13195-023-01332-4

Internet

https://doi.org/10.1186/s13195-023-01332-4

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