Extracellular vesicle microRNAs contribute to Notch signaling pathway in T-cell acute lymphoblastic leukemia

Extracellular vesicle microRNAs contribute to Notch signaling pathway in T-cell acute lymphoblastic leukemia

Abstract T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive T-cell malignancy characterized by genotypically-defined and phenotypically divergent cell populations, governed by adaptive landscapes. Clonal expansions are associated to genetic and epigenetic events, and modulation of external...

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Bibliographic Details
Main Authors: Tommaso Colangelo, Patrizio Panelli, Francesco Mazzarelli, Francesco Tamiro, Valentina Melocchi, Elisabetta De Santis, Roberto Cuttano, Orazio Palumbo, Giovanni Rossi, Fabrizio Bianchi, Vincenzo Giambra
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Molecular Cancer
Subjects:
T-cell acute lymphoblastic leukemia
microRNAs
Exosomes
Extracellular vesicles
Gene expression
Online Access:https://doi.org/10.1186/s12943-022-01698-3

Internet

https://doi.org/10.1186/s12943-022-01698-3

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