PON-SC – program for identifying steric clashes caused by amino acid substitutions
Abstract Background Amino acid substitutions due to DNA nucleotide replacements are frequently disease-causing because of affecting functionally important sites. If the substituting amino acid does not fit into the protein, it causes structural alterations that are often harmful. Clashes of amino ac...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-11-01
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| Series: | BMC Bioinformatics |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12859-017-1947-7 |