Canthin-6-one analogs block Newcastle disease virus proliferation via suppressing the Akt and ERK pathways

Canthin-6-one analogs block Newcastle disease virus proliferation via suppressing the Akt and ERK pathways

ABSTRACT: Newcastle disease virus, a member of the Paramyxoviridae family, causes significant economic losses in poultry worldwide. To identify novel antiviral agents against NDV, 36 canthin-6-one analogs were evaluated in this study. Our data showed that 8 compounds exhibited excellent inhibitory e...

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Bibliographic Details
Main Authors: Chongyang Wang, Ting Wang, Jiangkun Dai, Yu Han, Ruochen Hu, Na Li, Zengqi Yang, Junru Wang
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Poultry Science
Subjects:
antiviral
canthin-6-one
Newcastle disease virus
viral entry
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124005236

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http://www.sciencedirect.com/science/article/pii/S0032579124005236

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