Salivary microbiome changes distinguish response to chemoradiotherapy in patients with oral cancer

Abstract Background Oral squamous cell carcinoma (SCC) is associated with oral microbial dysbiosis. In this unique study, we compared pre- to post-treatment salivary microbiome in patients with SCC by 16S rRNA gene sequencing and examined how microbiome changes correlated with the expression of an a...

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Main Authors: Marcell Costa de Medeiros, Stephanie The, Emily Bellile, Nickole Russo, Ligia Schmitd, Erika Danella, Priyanka Singh, Rajat Banerjee, Christine Bassis, George R. Murphy, Maureen A. Sartor, Isabelle Lombaert, Thomas M. Schmidt, Avi Eisbruch, Carol Anne Murdoch-Kinch, Laura Rozek, Gregory T. Wolf, Gen Li, Grace Y. Chen, Nisha J. D’Silva
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Microbiome
Online Access:https://doi.org/10.1186/s40168-023-01677-w