Injectable hydrogel loaded with bilayer microspheres to inhibit angiogenesis and promote cartilage regeneration for repairing growth plate injury

Injectable hydrogel loaded with bilayer microspheres to inhibit angiogenesis and promote cartilage regeneration for repairing growth plate injury

Introduction: The repair and regeneration of growth plate injuries using tissue engineering techniques remains a challenge due to large bone bridge formation and low chondrogenic efficiency.Methods: In this study, a bilayer drug-loaded microspheres was developed that contains the vascular endothelia...

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Bibliographic Details
Main Authors: Lei Qiang, Minjie Fan, Yiwei Wang, Yihao Liu, Hanjie Zhuang, Ruoyi Guo, Hao Huang, Yulong Ben, Dalin Wang, Xiaoling Wu, Jinwu Wang, Jie Weng, Pengfei Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
growth plate
bilayer microspheres
anti-angiogenesis
chondrogenic differentiation
hydrogel
tissue engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1181580/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2023.1181580/full

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