The establishment of mitotic errors-driven senescence depends on autophagy

We and others have reported that senescence onset is accompanied by genomic instability that is evident by several defects, such as aneuploidy or erroneous mitosis features. Here, we report that these defects also appear in young cells upon oxidative insult. We provide evidence that these errors cou...

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Bibliographic Details
Main Authors: Andreas Goutas, Zozo Outskouni, Ioanna Papathanasiou, Aphrodite Georgakopoulou, Georgios E. Karpetas, Efstathios S. Gonos, Varvara Trachana
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723001027