A Three lncRNA Set: AC009975.1, POTEH-AS1 and AL390243.1 as Nodal Efficacy Biomarker of Neoadjuvant Therapy for HER-2 Positive Breast Cancer

A Three lncRNA Set: AC009975.1, POTEH-AS1 and AL390243.1 as Nodal Efficacy Biomarker of Neoadjuvant Therapy for HER-2 Positive Breast Cancer

PurposeThe study aimed to explore whether the expression of lncRNAs in primary tumors could predict nodal efficacy after neoadjuvant therapy (NAT) for HER2+ breast cancer.MethodsTotal RNA was extracted from HER2+ breast cancer tissues before NAT (n=103) and from 48 pairs of cancers and para-cancers...

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Bibliographic Details
Main Authors: Zhao Bi, Peng-Fei Qiu, Yue Zhang, Xing-Guo Song, Peng Chen, Li Xie, Yong-Sheng Wang, Xian-Rang Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Oncology
Subjects:
breast cancer
neoadjuvant therapy
HER-2
LncRNA-AC009975.1
POTEH-AS1
lncRNA-AL390243.1
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.779140/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.779140/full

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