RhoG’s Role in T Cell Activation and Function

RhoG’s Role in T Cell Activation and Function

The role of RhoG in T cell development is redundant with other Racs subfamily members, and this redundancy may be attributed to redundant signal transduction pathways. However, the absence of RhoG increases TCR signalling and proliferation, implying that RhoG activity is critical during late T cell...

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Bibliographic Details
Main Authors: Ana Masara Ahmad Mokhtar, Nor Hawani Salikin, Aminah Suhaila Haron, Syafinaz Amin-Nordin, Ilie Fadzilah Hashim, Muaz Mohd Zaini Makhtar, Siti Balqis Zulfigar, Nurul Izza Ismail
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
Small Rho GTPase
RhoG
T cell
cancer
hemophagocytic lymphohistiocytosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.845064/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.845064/full

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