Comparison of the Drug-Induced Efficacies between Omidenepag Isopropyl, an EP2 Agonist and PGF2α toward TGF-β2-Modulated Human Trabecular Meshwork (HTM) Cells

Comparison of the Drug-Induced Efficacies between Omidenepag Isopropyl, an EP2 Agonist and PGF2α toward TGF-β2-Modulated Human Trabecular Meshwork (HTM) Cells

To compare the drug-induced efficacies between omidenepag (OMD), an EP2 agonist, and prostaglandin F2α (PGF2α) on glaucomatous trabecular meshwork (TM) cells, two- and three-dimensional (2D and 3D) cultures of TGF-β2-modulated human trabecular meshwork (HTM) cells were used. The following analyses w...

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Bibliographic Details
Main Authors: Soma Suzuki, Masato Furuhashi, Yuri Tsugeno, Araya Umetsu, Yosuke Ida, Fumihito Hikage, Hiroshi Ohguro, Megumi Watanabe
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Journal of Clinical Medicine
Subjects:
3D spheroid cultures
human trabecular meshwork
omidenepag isopropyl
omidenepag
PGF2α
TGFβ2
Online Access:https://www.mdpi.com/2077-0383/11/6/1652

Internet

https://www.mdpi.com/2077-0383/11/6/1652

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