Adult neural stem cell fate is determined by thyroid hormone activation of mitochondrial metabolism

Objective: In the adult brain, neural stem cells (NSCs) located in the subventricular zone (SVZ) produce both neuronal and glial cells. Thyroid hormones (THs) regulate adult NSC differentiation towards a neuronal phenotype, but also have major roles in mitochondrial metabolism. As NSC metabolism rel...

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Bibliographic Details
Main Authors: J.D. Gothié, A. Sébillot, C. Luongo, M. Legendre, C. Nguyen Van, K. Le Blay, M. Perret-Jeanneret, S. Remaud, B.A. Demeneix
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817305689