Synthetic Approaches to a Challenging and Unusual Structure—An Amino-Pyrrolidine Guanine Core

The synthesis of an unreported 2-aminopyrrolidine-1-carboxamidine unit is here described for the first time. This unusual and promising structure was attained through the oxidative decarboxylation of amino acids using the pair of reagents, silver(I)/peroxydisulfate (Ag(I)/S<sub>2</sub>O&...

Full description

Bibliographic Details
Main Authors: Rafael Rippel, Luís Pinheiro, Mónica Lopes, Ana Lourenço, Luísa M. Ferreira, Paula S. Branco
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/4/797